DNA-REPAIR IN THE FISSION YEAST, SCHIZOSACCHAROMYCES-POMBE

被引：36

作者：

LEHMANN, AR ^{[1
]}

CARR, AM ^{[1
]}

WATTS, FZ ^{[1
]}

MURRAY, JM ^{[1
]}

机构：

[1] SUSSEX UNIV, SCH BIOL, MICROBIAL GENET LAB, BRIGHTON BN1 9RR, ENGLAND

来源：

MUTATION RESEARCH | 1991年 / 250卷 / 1-2期

基金：

英国医学研究理事会;

关键词：

DNA REPAIR IN S-POMBE; FISSION YEAST; DNA REPAIR IN;

D O I：

10.1016/0027-5107(91)90177-P

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Mutants of the fission yeast Schizosaccharomyces pombe which are sensitive to UV and/or gamma-irradiation have been assigned to 23 complementation groups, which can be assigned to three phenotypic groups. We have cloned genes which correct the deficiency in mutants corresponding to 12 of the complementation groups. Three genes in the excision-repair pathway have a high degree of sequence conservation with excision-repair genes from the evolutionarily distant budding yeast Saccharomyces cerevisiae. In contrast, those genes in the recombination repair pathway which have been characterised so far, show little homology with any previously characterised genes.

引用

页码：205 / 210

页数：6

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