LINKAGE ANALYSES USING BIOCHEMICAL VARIANTS IN MICE .2. LEVULINATE DEHYDRATASE AND AUTOSOMAL GLUCOSE 6-PHOSPHATE DEHYDROGENASE

The level of hepatic δ-aminolevulinate dehydratase varies among inbred strains of mice and is regulated by codominant alleles at the Lv locus. Twenty-two inbred strains have been classified with respect to this locus. Lv is 5±2 recombination units from brown, b, in linkage group VIII. The locus for autosomal glucose 6-phosphate dehydrogenase (Gpd-1) has also been assigned to linkage group VIII and is 32±5 units from brown. The order of the loci is Lv-b-Gpd-1. Incidental note is made of linkage between the malic dehydrogenase (Mdh-1) and dilute (d) loci, linkage group II, with 10±3 % recombination between the two. © 1969 Plenum Publishing Corporation.