INDUCTION OF THE CITROBACTER-FREUNDII GROUP-I BETA-LACTAMASE IN ESCHERICHIA-COLI IS NOT DEPENDENT ON ENTRY OF BETA-LACTAM INTO THE CYTOPLASM

被引：7

作者：

EVERETT, MJ

CHOPRA, I

BENNETT, PM

机构：

[1] Department of Microbiology, School of Medical Sciences, University of Bristol

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1990年 / 34卷 / 12期

关键词：

D O I：

10.1128/AAC.34.12.2429

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Induction of the cloned ampC Citrobacter freundii β-lactamase in Escherichia coli by 6-aminopenicillanic acid was prevented by periplasmic TEM β-lactamase in the same cell. In contrast, cytoplasmic TEM β-lactamase did not prevent induction. This result implies that entry of the β-lactam into the cytoplasm is not necessary for induction of ampC.

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页码：2429 / 2430

页数：2

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