ANTIBODIES TO SPOROZOITES - THEIR FREQUENT OCCURRENCE IN INDIVIDUALS LIVING IN AN AREA OF HYPER-ENDEMIC MALARIA

被引:169
作者
NARDIN, EH [1 ]
NUSSENZWEIG, RS [1 ]
MCGREGOR, IA [1 ]
BRYAN, JH [1 ]
机构
[1] MRC LAB,FAJARA,GAMBIA
关键词
D O I
10.1126/science.386511
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Serum samples from 158 West Africans were tested for antibodies against sporozoites, the vector stage of the malaria parasite. Antibodies specific for Plasmodium falciparum sporozoites were detected by means of the circumsporozoite precipitation assay and indirect immunofluorescence. More than 90 percent of the serum samples from adults gave positive immunofluorescent reactions against falciparum sporozoites, whereas most of the samples from children gave low or negative reactions. Copyright © 1979 AAAS.
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页码:597 / 599
页数:3
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