RADIOPROTECTIVE EFFECT OF VITAMIN-C AND VITAMIN-E

被引：76

作者：

ELNAHAS, SM ^{[1
]}

MATTAR, FE ^{[1
]}

MOHAMED, AA ^{[1
]}

机构：

[1] AL AZHAR UNIV, FAC MED, CAIRO, EGYPT

来源：

MUTATION RESEARCH | 1993年 / 301卷 / 02期

关键词：

VITAMIN-C; VITAMIN-E; RADIOPROTECTION;

D O I：

10.1016/0165-7992(93)90037-V

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Albino rats were treated with aqueous vitamin C solution and vitamin E solution dissolved in olive oil at two concentrations, 100 and 300 mg/kg/day, for 6 months. Some of the animals were then subjected to whole-body irradiation. Chromosomal aberrations and mitotic activity in non-irradiated and irradiated groups were recorded. Both vitamins were found to be non-mutagenic. Vitamin C exerted a radioprotective effect but vitamin E was not radioprotective and it suppressed the radioprotection otherwise produced by olive oil.

引用

页码：143 / 147

页数：5

共 31 条

[1] UPDATE ON THE EFFECTS OF VITAMIN-A, VITAMIN-C, AND VITAMIN-E AND SELENIUM ON CARCINOGENESIS
BIRT, DF
[J]. PROCEEDINGS OF THE SOCIETY FOR EXPERIMENTAL BIOLOGY AND MEDICINE, 1986, 183 (03): : 311 - 320
[2] Casarett AP, 1968, RAD BIOL
[3] RECOMBINATIONAL REPAIR OF HYDROGEN PEROXIDE-INDUCED DAMAGES IN DNA OF PHAGE-T4
CHEN, D
BERNSTEIN, C
[J]. MUTATION RESEARCH, 1987, 184 (02): : 87 - 98
[4] CHEN LH, 1988, ANTICANCER RES, V8, P739
[5] RADIOPROTECTIVE EFFECTS OF ASCORBIC-ACID IN BARLEY SEEDS
CONGER, BV
[J]. RADIATION BOTANY, 1975, 15 (01): : 39 - 48
[6] SINGLE-STRAND DNA BREAKS IN RODENT AND HUMAN-CELLS PRODUCED BY SUPEROXIDE ANION OR ITS REDUCTION PRODUCTS
CUNNINGHAM, ML
PEAK, JG
PEAK, MJ
[J]. MUTATION RESEARCH, 1987, 184 (03): : 217 - 222
[7] THE EFFECT OF DIETARY ASCORBIC-ACID AND ALPHA-TOCOPHEROL ON FECAL MUTAGENICITY
DION, PW
BRIGHTSEE, EB
SMITH, CC
BRUCE, WR
[J]. MUTATION RESEARCH, 1982, 102 (01): : 27 - 37
[8] DUCHESNE J, 1975, CR ACAD SCI D NAT, V281, P945
[9] Fridovich, 1976, FREE RADICALS BIOLOG, V1, P239
[10] VITAMIN-C IS POSITIVE IN THE DNA-SYNTHESIS INHIBITION AND SISTER-CHROMATID EXCHANGE TESTS
GALLOWAY, SM
PAINTER, RB
[J]. MUTATION RESEARCH, 1979, 60 (03): : 321 - 327

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