NOVEL INWARD RECTIFIER BLOCKED BY CD2+ IN CRAYFISH MUSCLE

被引：5

作者：

ARAQUE, A ^{[1
]}

BUNO, W ^{[1
]}

机构：

[1] CSK,INST CAJAL,AVE DOCTOR ARCE 37,E-28002 MADRID,SPAIN

来源：

BRAIN RESEARCH | 1991年 / 563卷 / 1-2期

关键词：

INWARD RECTIFIER; ANOMALOUS RECTIFICATION; CRAYFISH MUSCLE; CD2+-BLOCKADE; K+ CURRENT; HYPERPOLARIZATION-ACTIVATED CURRENT;

D O I：

10.1016/0006-8993(91)91555-F

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The characteristics of a voltage- and time-dependent inward rectifying current were examined with voltage clamp techniques in crayfish muscle. The inward current, carried by K+, was activated by hyperpolarization. Although this inward current increased with the extracellular K+ concentration ([K+]o), the voltage-dependence of the underlying conductance was independent of [K+]o. The current was unaffected by Cs+ and Ba2+, but was blocked by low concentrations of Cd2+. Therefore, this inward rectifier is different than previously described ones.

引用

页码：321 / 324

页数：4

共 27 条

[1]

BROWN HF, 1980, J PHYSIOL-LONDON, V308, P335

[2]

CHESNOYMARCHAIS D, 1982, NATURE, V299, P359

[3] FAST INWARD-RECTIFYING CURRENT ACCOUNTS FOR ANOMALOUS RECTIFICATION IN OLFACTORY CORTEX NEURONS [J].

CONSTANTI, A ;

GALVAN, M .

JOURNAL OF PHYSIOLOGY-LONDON, 1983, 335 (FEB) :153-178

[4] PROPERTIES OF THE CURRENT IF IN THE SINO-ATRIAL NODE OF THE RABBIT COMPARED WITH THOSE OF THE CURRENT IK2 IN PURKINJE-FIBERS [J].

DIFRANCESCO, D ;

OJEDA, C .

JOURNAL OF PHYSIOLOGY-LONDON, 1980, 308 (NOV) :353-367

[5] THE IONIC REQUIREMENTS FOR THE PRODUCTION OF ACTION POTENTIALS IN CRUSTACEAN MUSCLE FIBRES [J].

FATT, P ;

GINSBORG, BL .

JOURNAL OF PHYSIOLOGY-LONDON, 1958, 142 (03) :516-543

[6] ANOMALOUS RECTIFICATION AND CATION SELECTIVITY OF MEMBRANE OF A STARFISH EGG CELL [J].

HAGIWARA, S ;

TAKAHASHI, K .

JOURNAL OF MEMBRANE BIOLOGY, 1974, 18 (01) :61-80

[7] POTASSIUM CURRENT AND EFFECT OF CESIUM ON THIS CURRENT DURING ANOMALOUS RECTIFICATION OF EGG CELL-MEMBRANE OF A STARFISH [J].

HAGIWARA, S ;

MIYAZAKI, S ;

ROSENTHAL, NP .

JOURNAL OF GENERAL PHYSIOLOGY, 1976, 67 (06) :621-638

[8] BLOCKING EFFECTS OF BARIUM AND HYDROGEN-IONS ON POTASSIUM CURRENT DURING ANOMALOUS RECTIFICATION IN STARFISH EGG [J].

HAGIWARA, S ;

MIYAZAKI, S ;

MOODY, W ;

PATLAK, J .

JOURNAL OF PHYSIOLOGY-LONDON, 1978, 279 (JUN) :167-185

[9] CURRENT-VOLTAGE RELATIONS OF PURKINJE FIBRES IN SODIUM-DEFICIENT SOLUTIONS [J].

HALL, AE ;

HUTTER, OF ;

NOBLE, D .

JOURNAL OF PHYSIOLOGY-LONDON, 1963, 166 (01) :225-&

[10] VOLTAGE-CLAMP ANALYSIS OF MUSCARINIC EXCITATION IN HIPPOCAMPAL-NEURONS [J].

HALLIWELL, JV ;

ADAMS, PR .

BRAIN RESEARCH, 1982, 250 (01) :71-92

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