IMMUNOGLOBULIN-G, IMMUNOGLOBULIN-A AND IMMUNOGLOBULIN-M LIGHT CHAIN RATIO IN CHILDREN

被引：9

作者：

HARALDSSON, A

WEEMAES, CMR

KOCKJANSEN, MJH

VONECKARTS, PBJM

DEBOO, T

BAKKEREN, JAJM

STOELINGA, GBA

机构：

[1] UNIV HOSP NIJMEGEN,DEPT PAEDIAT,NIJMEGEN,NETHERLANDS

[2] UNIV HOSP NIJMEGEN,CENT CLIN CHEM LAB,NIJMEGEN,NETHERLANDS

[3] UNIV HOSP NIJMEGEN,DEPT MED STAT,NIJMEGEN,NETHERLANDS

来源：

ANNALS OF CLINICAL BIOCHEMISTRY | 1992年 / 29卷

基金：

美国国家科学基金会;

关键词：

KAPPA CHAINS; LAMBDA CHAINS; REFERENCE VALUES;

D O I：

10.1177/000456329202900303

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

Values for the kappa/lambda-light chain ratio in immunoglobulins G, A and M and the total kappa/lambda-ratio, measured by enzyme linked immunosorbent assay, were evaluated in serum samples from different age groups (114 children, aged from 1 month to 15 years, and 20 adults). The IgG kappa/lambda-ratio decreased in the first 6 months and subsequently increased slowly during childhood towards the adult value of 2.0. The IgM kappa/lambda-ratio increased at a greater rate than IgG kappa/lambda-ratio in the first years of life and thereafter rose slightly throughout childhood to reach an adult value of 1.7. A decreasing IgA kappa/lambda-ratio was found from 1 month of age onwards to an adult value of 1.1. The pattern of total kappa/lambda-ratio was similar to the IgG kappa/lambda-ratio with an adult value of 2.0.

引用

页码：271 / 274

页数：4

共 17 条

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