C-13 NMR EVIDENCE FOR 3 SLOWLY INTERCONVERTING CONFORMATIONS OF THE DIHYDROFOLATE REDUCTASE-NADP+-FOLATE COMPLEX

被引：18

作者：

BIRDSALL, B ^{[1
]}

GRONENBORN, A ^{[1
]}

CLORE, GM ^{[1
]}

ROBERTS, GCK ^{[1
]}

FEENEY, J ^{[1
]}

BURGEN, ASV ^{[1
]}

机构：

[1] NATL INST MED RES,DIV MOLEC PHARMACOL,LONDON NW7 1AA,ENGLAND

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1981年 / 101卷 / 04期

关键词：

D O I：

10.1016/0006-291X(81)91566-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：1139 / 1144

页数：6

共 18 条

[1] THE BINDING OF TRIMETHOPRIM TO BACTERIAL DIHYDROFOLATE-REDUCTASE
BAKER, DJ
BEDDELL, CR
CHAMPNESS, JN
GOODFORD, PJ
NORRINGTON, FEA
SMITH, DR
STAMMERS, DK
[J]. FEBS LETTERS, 1981, 126 (01) : 49 - 52
[2] BINDING OF COENZYME ANALOGS TO LACTOBACILLUS-CASEI DIHYDROFOLATE-REDUCTASE - BINARY AND TERNARY COMPLEXES
BIRDSALL, B
BURGEN, ASV
ROBERTS, GCK
[J]. BIOCHEMISTRY, 1980, 19 (16) : 3723 - 3731
[3] BIRDSALL B, UNPUBLISHED
[4] BLAKLEY RL, 1978, BIOCHEMISTRY-US, V17, P2284, DOI 10.1021/bi00605a005
[5] NUCLEAR MAGNETIC-RESONANCE STUDIES ON BACTERIAL DIHYDROFOLATE-REDUCTASE CONTAINING [GUANIDINO-C-13] ARGININE
COCCO, L
BLAKLEY, RL
WALKER, TE
LONDON, RE
MATWIYOFF, NA
[J]. BIOCHEMISTRY, 1978, 17 (20) : 4285 - 4290
[6] LARGE-SCALE PURIFICATION AND CHARACTERIZATION OF DIHYDROFOLATE-REDUCTASE FROM A METHOTREXATE-RESISTANT STRAIN OF LACTOBACILLUS-CASEI
DANN, JG
OSTLER, G
BJUR, RA
KING, RW
SCUDDER, P
TURNER, PC
ROBERTS, GCK
BURGEN, ASV
HARDING, NGL
[J]. BIOCHEMICAL JOURNAL, 1976, 157 (03) : 559 - 571
[7] KINETICS OF LIGAND-BINDING TO DIHYDROFOLATE-REDUCTASE - BINARY COMPLEX-FORMATION WITH NADPH AND COENZYME ANALOGS
DUNN, SMJ
BATCHELOR, JG
KING, RW
[J]. BIOCHEMISTRY, 1978, 17 (12) : 2356 - 2364
[8] H-1 NUCLEAR MAGNETIC-RESONANCE STUDIES OF TYROSINE RESIDUES OF SELECTIVELY DEUTERATED LACTOBACILLUS-CASEI DIHYDROFOLATE-REDUCTASE
FEENEY, J
ROBERTS, GCK
BIRDSALL, B
GRIFFITHS, DV
KING, RW
SCUDDER, P
BURGEN, A
[J]. PROCEEDINGS OF THE ROYAL SOCIETY SERIES B-BIOLOGICAL SCIENCES, 1977, 196 (1124): : 267 - 290
[9] P-31 NMR-STUDIES OF NADPH AND NADP+ BINDING TO L-CASEI DIHYDROFOLATE-REDUCTASE
FEENEY, J
BIRDSALL, B
ROBERTS, GCK
BURGEN, ASV
[J]. NATURE, 1975, 257 (5527) : 564 - 566
[10] DIRECT OBSERVATION BY NMR OF 2 COEXISTING CONFORMATIONS OF AN ENZYME-LIGAND COMPLEX IN SOLUTION
GRONENBORN, A
BIRDSALL, B
HYDE, EI
ROBERTS, GCK
FEENEY, J
BURGEN, ASV
[J]. NATURE, 1981, 290 (5803) : 273 - 274

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