PRODUCTION OF ANTIBODIES TO CATECHOL-O-METHYLTTANSFERASE (EC 2.1.1.6) OF RAT LIVER

被引:17
作者
ASSICOT, M
BOHUON, C
机构
[1] Laboratoire de Biologie Clinique et Expérimentale, Institut Gustave Roussy
关键词
D O I
10.1016/0006-2952(69)90284-6
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
A potent and specific antibody to the catechol-O-methyltransferase (EC 2.1.1.6) has been produced in rabbits by injecting the purified enzyme from rat liver. This antibody inhibited the catechol-O-methyltransferase from various organs of the rat and from liver of some mammalian species. The specificity of the antibody was demonstrated by the lack of inhibition of several other O-ethylating enzymes. The usefulness of this antibody for pharmacological research is emphasized. © 1969.
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页码:1893 / &
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