MICROSOMAL THYROXINE MEASUREMENTS WITH IODIDE SELECTIVE MEMBRANE ELECTRODES

被引：7

作者：

MEYERHOFF, ME ^{[1
]}

RECHNITZ, GA ^{[1
]}

机构：

[1] UNIV DELAWARE,DEPT CHEM,NEWARK,DE 19711

来源：

ANALYTICAL LETTERS PART A-CHEMICAL ANALYSIS | 1979年 / 12卷 / 13期

关键词：

D O I：

10.1080/00032717908067924

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

An iodide membrane electrode, in conjunction with rat liver microsomes, is used to measure thyroxine at sub-micromolar levels. The microsomes serve as biocatalytic reagents which selectively remove iodide from the hormone. The amount of iodide liberated, as measured by the electrode, is proportional to the initial thyroxine concentration. The electrode can further be employed to directly monitor the rate of deiodination of the hormone with advantages of speed and convenience over existing techniques. Copyright © 1979 by Marcel Dekker, Inc. All Rights Reserved

引用

页码：1339 / 1346

页数：8

共 7 条

[1] MEMBRANE ELECTRODE MEASUREMENT OF LYSOZYME ENZYME USING LIVING BACTERIAL-CELLS
DORAZIO, P
MEYERHOFF, ME
RECHNITZ, GA
[J]. ANALYTICAL CHEMISTRY, 1978, 50 (11) : 1531 - 1534
[2] DEGRADATION OF THYROXINE BY MICROSOMAL PARTICLES FROM RAT LIVER .1. CORRELATION BETWEEN THYROXINE DEGRADATION AND LIPID PEROXIDES
NAKANO, M
TSUTSUMI, Y
USHIJIMA, Y
[J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1971, 252 (02) : 335 - +
[3] BIO-SELECTIVE MEMBRANE-ELECTRODE USING TISSUE-SLICES
RECHNITZ, GA
ARNOLD, MA
MEYERHOFF, ME
[J]. NATURE, 1979, 278 (5703) : 466 - 467
[4] RECHNITZ GA, 1978, SCIENCE, V199, P140
[5] DEGRADATION OF THYROXINE BY MICROSOMAL PARTICLES FROM RAT-LIVER .2. PURIFICATION OF FE2+-DEPENDENT PARTICLES AND SOME OF THEIR PROPERTIES
USHIJIMA, Y
SUWA, K
NAKANO, M
[J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1973, 320 (02) : 284 - 294
[6] WILKINSON JH, 1955, BIOCH J, V56, P215
[7] WYNN J, 1962, J BIOL CHEM, V237, P1892

← 1 →