ARE ACCESSORY MOLECULES IMPLICATED IN ACTIVATION OF T-CELLS AT THE BLOOD-RETINAL BARRIER

被引：10

作者：

LIVERSIDGE, J

FORRESTER, JV

机构：

[1] Department of Ophthalmology, University of Aberdeen, Aberdeen

来源：

CURRENT EYE RESEARCH | 1990年 / 9卷

基金：

英国惠康基金;

关键词：

D O I：

10.3109/02713689008999432

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Co-culture of rat retinal pigment epithelial (RPE) cells or retinal capillary endothelial (EC) cells with T lymphocytes from immunised syngeneic rats indicated that RPE cells but not EC could process retinal S-antigen and induce antigen specific T cell activation. Activation of lymphocytes by EC however was also antigen independent, and may be due to T cell (CD2) endothelial cell (LFA-3) ligand interactions which are functional on EC but not RPE. © 1990 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.

引用

页码：131 / 134

页数：4

共 14 条

[1] COTRANSFECTION OF ICAM-1 AND HLA-DR RECONSTITUTES HUMAN ANTIGEN-PRESENTING CELL-FUNCTION IN MOUSE L-CELLS [J].