SYNTHESIS OF PYRIMIDO[2,1-B]THIAZIN-6-ONE BY RETRO DIELS-ALDER REACTION

被引：17

作者：

FULOP, F

HUBER, I

SZABO, A

BERNATH, G

SOHAR, P

机构：

[1] ALBERT SZENT GYORGYI MED UNIV,INST PHARMACEUT CHEM,POB 121,H-6701 SZEGED,HUNGARY

[2] EGIS PHARMACEUT,DEPT SPECTROSCOP,H-1475 BUDAPEST,HUNGARY

来源：

TETRAHEDRON | 1991年 / 47卷 / 36期

关键词：

THIAZOLO[2,3-B]QUINAZOLIN-5-ONE; THIAZINO[2,3-B]QUINAZOLIN-6-ONE; RETRODIENE DECOMPOSITION; THIAZOLO[3,2-A]PYRIMIDIN-5-ONE; PYRIMIDO[2,1-B]THIAZIN-6-ONE;

D O I：

10.1016/S0040-4020(01)88290-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The first mild retrodiene processes resulting in bicyclic heterocycles are described. From norbornene diexo- and diendo-beta-amino acids with chloroalkyl isothiocyanates, compounds 3-6 were prepared, which, by retrodiene decomposition, furnished 7 and 8.

引用

页码：7673 / 7676

页数：4

共 19 条

[1] STEREOCHEMICAL STUDIES .107. SATURATED HETEROCYCLES .111. PREPARATION OF URACILS VIA CYCLOREVERSION OF NORBORNENE-FUSED PYRIMIDINEDIONES
BERNATH, G
STAJER, G
SZABO, AE
SZOKEMOLNAR, Z
SOHAR, P
ARGAY, G
KALMAN, A
[J]. TETRAHEDRON, 1987, 43 (08) : 1921 - 1930
[2] DIE DARSTELLUNG VON BETA-CHLOR-ATHYL-AMIDEN UND BIS-[BETA-CHLOR-ATHYL]-AMIDEN VERSCHIEDENER SAUREN
BRINTZINGER, H
PFANNSTIEL, K
KODDEBUSCH, H
[J]. CHEMISCHE BERICHTE-RECUEIL, 1949, 82 (4-5): : 389 - 399
[3] SYNTHESIS AND REACTIONS OF THIAZOLIDINO[3,2-A]PYRIMIDINES
BROWN, GR
DYSON, WR
[J]. JOURNAL OF THE CHEMICAL SOCIETY C-ORGANIC, 1971, (08): : 1527 - &
[4] REACTION OF ANTHRANILAMIDE WITH ISOTHIOCYANATE - A ONE-POT SYNTHESIS OF 2,3-DIHYDRO-5H-THIAZOLO[2,3-B]QUINAZOLIN-5-ONE
CHERN, JW
LIU, KC
SHISH, FJ
CHAN, CH
[J]. ARCHIV DER PHARMAZIE, 1987, 320 (12) : 1276 - 1277
[5] KINOSHITA T, 1987, CHEM PHARM BULL, V35, P90
[6] SYNTHESIS AND ANTIALLERGY ACTIVITY OF 5-OXO-5H-THIAZOLO[2,3-B]QUINAZOLINECARBOXYLIC ACIDS
LEMAHIEU, RA
CARSON, M
WELTON, AF
BARUTH, HW
YAREMKO, B
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1983, 26 (01) : 107 - 110
[7] SYNTHESIS AND ANTIHYPERTENSIVE ACTIVITY OF SOME QUINAZOLINONE DERIVATIVES
LIU, KC
HSU, LY
[J]. ARCHIV DER PHARMAZIE, 1985, 318 (06) : 502 - 505
[8] NEW ONE-STEP SYNTHESIS OF 2,3-DIHYDRO-5H-THIAZOLO[2,3-B]QUINAZOLIN-5-ONE AND 3,4-DIHYDRO-2H,6H[1,3]THIAZINO[2,3-B]QUINAZOLIN-6-ONE
PAYNE, LG
PRZYTYCKI, J
PATCHETT, AA
WU, MT
[J]. JOURNAL OF HETEROCYCLIC CHEMISTRY, 1979, 16 (02) : 391 - 391
[9] PECORARI P, 1989, J HETEROCYCLIC CHEM, V26, P1701
[10] ELECTRON IONIZATION MASS-SPECTRA OF SOME CYCLOHEXANE FUSED 2-N-PHENYLIMINOPERHYDRO-1,3-OXAZINES AND RELATED THIAZINES
PIHLAJA, K
LOTJONEN, L
FULOP, F
BERNATH, G
VAINIOTALO, P
[J]. RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 1990, 4 (08) : 279 - 282

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