EGF: new tricks for an old growth factor

被引：29

作者：

Carpenter, Graham ^{[1
]}

机构：

[1] Vanderbilt Univ, Sch Med, Dept Biochem, Nashville, TN 37232 USA

来源：

CURRENT OPINION IN CELL BIOLOGY | 1993年 / 5卷 / 02期

关键词：

D O I：

10.1016/0955-0674(93)90113-5

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

During the past year, the biology of epidermal growth factor (EGF) has been investigated in lower organisms (Caenorhabditis elegans, Drosophila and bacteria). These experiments have produced some surprising results: the identification of defects produced by mutation of EGF-like genes; the role of EGF receptors in bacterial invasion; and the role of EGF-like precursors as receptors for a bacteria toxin.

引用

页码：261 / 264

页数：4

共 28 条

[1] THE LET-23 GENE NECESSARY FOR CAENORHABDITIS-ELEGANS VULVAR INDUCTION ENCODES A TYROSINE KINASE OF THE EGF RECEPTOR SUBFAMILY
AROIAN, RV
KOGA, M
MENDEL, JE
OHSHIMA, Y
STERNBERG, PW
[J]. NATURE, 1990, 348 (6303) : 693 - 699
[2] CAENORHABDITIS-ELEGANS RAS GENE LET-60 ACTS AS A SWITCH IN THE PATHWAY OF VULVAR INDUCTION
BEITEL, GJ
CLARK, SG
HORVITZ, HR
[J]. NATURE, 1990, 348 (6301) : 503 - 509
[3] CARPENTER G, 1990, J BIOL CHEM, V265, P7709
[4] I125 LABELED HUMAN EPIDERMAL GROWTH-FACTOR - BINDING, INTERNALIZATION, AND DEGRADATION IN HUMAN FIBROBLASTS
CARPENTER, G
COHEN, S
[J]. JOURNAL OF CELL BIOLOGY, 1976, 71 (01) : 159 - 171
[5] Carpenter G., 1990, HDB EXPT PHARM, P69
[6] C-ELEGANS CELL-SIGNALING GENE SEM-5 ENCODES A PROTEIN WITH SH2 AND SH3 DOMAINS
CLARK, SG
STERN, MJ
HORVITZ, HR
[J]. NATURE, 1992, 356 (6367) : 340 - 344
[7] COHEN S, 1962, J BIOL CHEM, V237, P1555
[8] THE INTERACTION OF BACTERIA WITH MAMMALIAN-CELLS
FALKOW, S
ISBERG, RR
PORTNOY, DA
[J]. ANNUAL REVIEW OF CELL BIOLOGY, 1992, 8 : 333 - 363
[9] INVOLVEMENT OF THE EPIDERMAL GROWTH-FACTOR RECEPTOR IN THE INVASION OF CULTURED-MAMMALIAN-CELLS BY SALMONELLA-TYPHIMURIUM
GALAN, JE
PACE, J
HAYMAN, MJ
[J]. NATURE, 1992, 357 (6379) : 588 - 589
[10] THE ROLES OF SH2/SH3 DOMAINS IN NEMATODE DEVELOPMENT
GOLDEN, A
STERNBERG, PW
[J]. BIOESSAYS, 1992, 14 (07) : 481 - 484

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