Cellular aging and senescence

被引：54

作者：

McCormick, Anna ^{[1
]}

Campisi, Judith ^{[2
]}

机构：

[1] NIA, Biol Aging Program, Bethesda, MD 20892 USA

[2] Univ Calif Berkeley, Lawrence Berkeley Natl Lab, Div Cell & Mol Biol, Berkeley, CA 94720 USA

来源：

CURRENT OPINION IN CELL BIOLOGY | 1991年 / 3卷 / 02期

关键词：

D O I：

10.1016/0955-0674(91)90144-N

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Differentiated eukaryotic cells have only a finite capacity for cell division. This limitation is thought to be a cellular manifestation of organismal aging, and a restraint to tumor progression. The molecular basis for cellular senescence is not known, but a molecular framework for understanding this phenomenon has recently been established.

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收藏

页码：230 / 234

页数：5

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