CHANGES IN MIXED LYMPHOCYTE CULTURE (MLC) FUNCTIONS OF PERIPHERAL LYMPHOID-CELLS AFTER RADIATION-THERAPY FOR BREAST CARCINOMA

被引：17

作者：

BLOMGREN, H ^{[1
]}

WASSERMAN, J ^{[1
]}

WALLGREN, A ^{[1
]}

IDESTROM, K ^{[1
]}

BARAL, E ^{[1
]}

PETRINI, B ^{[1
]}

机构：

[1] STOCKHOLM CTY COUNCIL,CENT MICROBIOL LAB,S-10122 STOCKHOLM,SWEDEN

来源：

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS | 1979年 / 5卷 / 01期

关键词：

Activated monocytes; Inhibitor cells; Inhibitory monocytes; Lymphopenia; MLC reactivity; Radiation therapy; Suppressor cells;

D O I：

10.1016/0360-3016(79)90037-3

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Peripheral lymphoid cells of patients with breast cancer were tested for their capacity to function as andstimulators in mixed lymphocyte culture (MLC before and after local radir local radiation therapy. Both of these MLC functions were decreased after therapy and returned to pretreatment levels within 3-4 months. Both the responder and stimulator capacities of the cell preparations obtained at completion of radiation therapy were increased by depleting phagocytic cells. These results are consistent with the view that immunosuppression observed shortly after radiation therapy results partly from the appearance of non-specific suppressor cells with monocyte characteristics. © 1979.

引用

页码：49 / 53

页数：5

共 26 条

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