PARTIAL AMINO-ACID SEQUENCE OF 2 FORMS OF HUMAN POST-GAMMA-GLOBULIN

We have purified two different electrophoretic forms of Post-γ-globulin defined by electrophoresis as native slow" form and "fast" form respectively. Amino acid sequences of the first fifty-two residues of the "native slow" form and twenty-nine of the "fast" form were determined. The sequence shows that the "fast" form lacks the first nine amino acids of the "native slow" form. This observation is consistent with the existence of a "native slow" form that is degraded into other more acidic forms of Post-γ-globulin by loss of basic amino acids. © 1979."