EPOXIDES - COMPARISON OF THE INDUCTION OF SOS REPAIR IN ESCHERICHIA-COLI PQ37 AND THE BACTERIAL MUTAGENICITY IN THE AMES TEST

被引：25

作者：

VONDERHUDE, W ^{[1
]}

SEELBACH, A ^{[1
]}

BASLER, A ^{[1
]}

机构：

[1] FREE UNIV BERLIN,INST ALLGEMEINE GENET,W-1000 BERLIN 33,GERMANY

来源：

MUTATION RESEARCH | 1990年 / 231卷 / 02期

关键词：

Ames test; Epoxides; SOS-Chromotest;

D O I：

10.1016/0027-5107(90)90027-2

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The genotoxicity of 51 epoxides is studied with SOS-Chromotest using Escherichia coli PQ37 as tester strain. The results obtained with this test system are compared with results of the Ames test. Out pf 51 epoxides, 39 are shown to be mutagenic in Salmonella typhimurium whereas only 27 mutagenic epoxides induced the SOS response in Escherichia coli PQ37. © 1990.

引用

页码：205 / 218

页数：14

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