THE FADD GENE OF ESCHERICHIA-COLI K12 IS LOCATED CLOSE TO RND AT 39.6 MIN OF THE CHROMOSOMAL MAP AND IS A NEW MEMBER OF THE AMP-BINDING PROTEIN FAMILY

被引：73

作者：

FULDA, M ^{[1
]}

HEINZ, E ^{[1
]}

WOLTER, FP ^{[1
]}

机构：

[1] UNIV HAMBURG, INST ALLGEMEINE BOT, D-22609 HAMBURG, GERMANY

来源：

MOLECULAR AND GENERAL GENETICS | 1994年 / 242卷 / 03期

关键词：

FADD; ACYL-COA SYNTHETASE; AMP-BINDING; ESCHERICHIA COLI K12; SEQUENCE;

D O I：

10.1007/BF00280412

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The fadD gene of Escherichia coli K12 was cloned and sequenced. The gene was identified by its ability to complement the corresponding mutant and by measuring the enzymatic activity after its expression in this mutant. The deduced polypeptide sequence exhibits similarity to other long chain acyl-CoA (coenzyme A) synthetases and a variety of other proteins, which together form a family of AMP-binding proteins. This family is extended by several new members and subdivided into four groups. fadD is assigned to a subgroup that does not include long chain acyl-CoA synthetases from eukaryotic organisms.

引用

页码：241 / 249

页数：9

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