CORNIFIED CELL-ENVELOPE

被引:165
作者
HOHL, D
机构
[1] NCI,DERMATOL BRANCH,BETHESDA,MD 20205
[2] BAYLOR UNIV,DEPT CELL BIOL,HOUSTON,TX 77030
来源
DERMATOLOGICA | 1990年 / 180卷 / 04期
关键词
cornified cell envelope; dense homogeneous deposits; epidermis; involucrin; keratinocyte; keratohyaline; loricrin; marginal band; skin; transglutaminase;
D O I
10.1159/000248031
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
The cornified cell envelope (CE) is a highly insoluble structure on the inside of the plasma membrane of terminally differentiated keratinocytes. The cellular and molecular biology of the CE is outlined and new areas of research involving the CE are reviewed focussing on morphological and biochemical connections, the sequential gene expression during terminal differentiation, the interaction of lipids and proteins forming the epidermal barrier, the cysteine-rich pool of proteins in the epidermis as well as the molecular cloning and/or characterization of major components of the CE.
引用
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页码:201 / 211
页数:11
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