TRIFLUOROMETHYLATED HETEROCYCLES FROM BETA-TRIFLUOROACETYL-LACTAMS AND BETA-TRIFLUOROBENZOLACTAMS

被引：40

作者：

BOUILLON, JP ^{[1
]}

ATES, C ^{[1
]}

JANOUSEK, Z ^{[1
]}

VIEHE, HG ^{[1
]}

机构：

[1] LAB CHIM ORGAN,PL L PASTEUR 1,B-1348 LOUVAIN,BELGIUM

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 32期

关键词：

D O I：

10.1016/S0040-4039(00)60679-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Trifluoromethyl substituted heterocycles have been prepared by condensation of the new beta-trifluoroacetyl-lactams 1 and -benzolactams 2 with methylhydrazine and benzamidine as bis-nucleophiles without opening of the lactam structure.

引用

页码：5075 / 5078

页数：4

共 9 条

[1] INHIBITION-KINETICS OF ACETYLCHOLINESTERASE WITH FLUOROMETHYL KETONES
ALLEN, KN
ABELES, RH
[J]. BIOCHEMISTRY, 1989, 28 (21) : 8466 - 8473
[2] ATTEMPT TO APPLY LETHAL SYNTHESIS TO THE DESIGN OF CHEMOTHERAPEUTIC-AGENTS - FLUORINATED 5 BETA-(HYDROXYETHYL)-4-METHYLTHIAZOLES
ARCHER, S
PERIANAYAGAM, C
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1979, 22 (03) : 306 - 309
[3] TRIFLUOROMETHYLATION OF ALIPHATIC HALOGEN COMPOUNDS
BOUILLON, JP
MALIVERNEY, C
MERENYI, R
VIEHE, HG
[J]. JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1991, (09): : 2147 - 2149
[4] EBRAHEEM KAK, 1981, CAN J SPECTROSC, V26, P225
[5] Filler R., 1982, BIOMEDICAL ASPECTS F
[6] FOMIN AN, 1986, ZH ORG KHIM+, V22, P1603
[7] SOME COMPOUNDS CONTAINING THE TRIFLUOROMETHYL GROUP
GILMAN, H
TOLMAN, L
YEOMAN, F
WOODS, LA
SHIRLEY, DA
AVAKIAN, S
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1946, 68 (03) : 426 - 428
[8] KNUNYANTS IL, 1986, IAN SSSR KH, V7, P1688
[9] Welch T., 1991, FLUORINE BIOORGANIC

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