EARLY DETECTION OF OVARIAN-CANCER

被引:49
作者
TENERIELLO, MG
PARK, RC
机构
[1] Medical College of Pennsylvania, Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Allegheny General Hospital in Pittsburgh, Pennsylvania
[2] Gynecologic Oncology Group, Uniformed Services University of the Health Sciences, Department of Obstetrics and Gynecology, Walter Reed Army Medical Center in Washington, Washington, District of Columbia
关键词
D O I
10.3322/canjclin.45.2.71
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Ovarian cancer meets the criteria of a disease for which screening can be justified. The disease is most often diagnosed in advanced stages, when chances for long-term survival are poor. Yet effective treatment exists for early-stage disease, such that early detection can increase long-term survival. However, screening for early-stage ovarian cancer with the high specificity necessary for this low-prevalence disease has proven to be a challenge. This article reviews the issues of early detection of ovarian cancer, including pathology, statistical considerations, diagnostic modalities, and results of the major clinical studies undertaken.
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收藏
页码:71 / 87
页数:17
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  • [1] Wingo PA, Tong T, Bolden S, Cancer statistics, 1995, CA Cancer J Clin, 45, pp. 8-30, (1995)
  • [2] Ozols RF, Rubin SC, Dembo AJ, Robboy SJ, Epithelial ovarian cancer, Principles and Practice of Gynecologic Oncology, pp. 731-781, (1992)
  • [3] Morrow CP, Malignant and borderline epithelial tumors of the ovary: clinical features, staging, diagnosis, intraoperative assessment and review of management, Gynecologic Oncology: Fundamental Principles and Clinical Practice, pp. 889-915, (1992)
  • [4] Westhoff C, Randall MC, Ovarian cancer screening: Potential effect on mortality, Am J Obstet Gynecol, 165, pp. 502-505, (1991)
  • [5] Hart WR, Pathology of malignant and borderline (low malignant potential) epithelial tumors of the ovary, Gynecologic Oncology: Fundamental Principles and Clinical Practice, pp. 863-887, (1992)
  • [6] Massad LS, Hunter VJ, Szpak CA, Et al., Epithelial ovarian tumors of low malignant potential, Obstet Gynecol, 78, pp. 1027-1032, (1991)
  • [7] Puls LE, Powell DE, DePriest PD, Et al., Transition from benign to malignant epithelium in mucinous and serous ovarian cystadenocarcinoma, Gynecol Oncol, 47, pp. 53-57, (1992)
  • [8] DePriest PD, van Nagell JR, Gallion HH, Et al., Ovarian cancer screening in asymptomatic post‐menopausal women, Gynecol Oncol, 51, pp. 205-209, (1993)
  • [9] Bell DA, Scully RE, Early de novo ovarian carcinoma: A study of 14 cases, Cancer, 73, pp. 1859-1864, (1994)
  • [10] Barber HK, Graber EA, The PMPO syndrome (postmenopausal palpable ovary syndrome), Obstet Gynecol, 38, pp. 921-923, (1971)