IN-VIVO P-31 NMR MEASUREMENT OF GLUCOSE-6-PHOSPHATE IN THE RAT MUSCLE AFTER EXERCISE

被引:38
作者
BLOCH, G
CHASE, JR
AVISON, MJ
SHULMAN, RG
机构
[1] YALE UNIV,DEPT MOLEC BIOPHYS & BIOCHEM,333 CEDAR ST,POB 3333,NEW HAVEN,CT 06510
[2] YALE UNIV,DEPT INTERNAL MED,NEW HAVEN,CT 06510
关键词
GLYCOGEN; GASTROCNEMIUS; GLYCOGEN SYNTHESIS;
D O I
10.1002/mrm.1910300311
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Comparison of P-31 NMR spectra of the rat gastrocnemius, obtained in vivo and from PCA extracts, after electrically induced contractions, demonstrates that glucose-6-phosphate (G6P) is the major metabolite in the low-field part of the PME spectral region. In vivo P-31 NMR can thus be used to measure the muscle G6P concentration after exercise.
引用
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页码:347 / 350
页数:4
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