UPTAKE AND METABOLISM OF EXOGENOUS AND ENDOGENOUS THYROXINE IN THE BRAIN OF YOUNG-RATS

被引：35

作者：

VIGOUROUX, E ^{[1
]}

CLOS, J ^{[1
]}

LEGRAND, J ^{[1
]}

机构：

[1] UNIV MONTPELLIER 2, PHYSIOL COMPAREE LAB, F-34060 MONTPELLIER, FRANCE

来源：

HORMONE AND METABOLIC RESEARCH | 1979年 / 11卷 / 03期

关键词：

D O I：

10.1055/s-0028-1092714

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The uptake of labelled exogenous thyroxine by the brain was determined in 10- and 30-day-old rats. It was three times higher and thyroxine was more deiodinated on day 10 than on day 30. On the other hand, the endogenous hormonal iodine content was estimated in both the brain and the isolated cortical neurones in young rats of the same ages equilibrated with 125I. On day 10, brain and neurones contained five times more thyroid hormones than on day 30. These results are discussed in the context of the relations previously discovered between development of thyroid function and brain maturation.

引用

页码：228 / 232

页数：5

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