SYNTHESIS AND ANTIHERPETIC ACTIVITY OF (+/-)-9-[[(Z)-2-(HYDROXYMETHYL)CYCLOPROPYL]METHYL]GUANINE AND RELATED-COMPOUNDS

被引：90

作者：

ASHTON, WT ^{[1
]}

MEURER, LC ^{[1
]}

CANTONE, CL ^{[1
]}

FIELD, AK ^{[1
]}

HANNAH, J ^{[1
]}

KARKAS, JD ^{[1
]}

LIOU, R ^{[1
]}

PATEL, GF ^{[1
]}

PERRY, HC ^{[1
]}

WAGNER, AF ^{[1
]}

WALTON, E ^{[1
]}

TOLMAN, RL ^{[1
]}

机构：

[1] MERCK SHARP & DOHME RES LABS,W POINT,PA 19486

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1988年 / 31卷 / 12期

关键词：

D O I：

10.1021/jm00120a010

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：2304 / 2315

页数：12

共 56 条

[31] POTENTIAL PURINE ANTAGONISTS .19. SYNTHESIS OF SOME 9-ALKYL(ARYL)-2-AMINO-6-SUBSTITUTED PURINES AND RELATED V-TRIAZOLO[D]PYRIMIDINES
KOPPEL, HC
OBRIEN, DE
ROBINS, RK
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1959, 81 (12) : 3046 - 3051
[32] KRITSYN AM, 1975, MOLEK BIOL, V9, P121
[33] MODE OF ACTION, TOXICITY, PHARMACOKINETICS, AND EFFICACY OF SOME NEW ANTIHERPES-VIRUS GUANOSINE ANALOGS RELATED TO BUCICLOVIR
LARSSON, A
STENBERG, K
ERICSON, AC
HAGLUND, U
YISAK, WA
JOHANSSON, NG
OBERG, B
DATEMA, R
[J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1986, 30 (04) : 598 - 605
[34] ANTIHERPETIC ACTIVITY AND MECHANISM OF ACTION OF 9-(4-HYDROXYBUTYL)GUANINE
LARSSON, A
ALENIUS, S
JOHANSSON, NG
OBERG, B
[J]. ANTIVIRAL RESEARCH, 1983, 3 (02) : 77 - 86
[35] MACCOSS M, 1986, CHEM SCRIPTA, V26, P113
[36] 9-[(1,3-DIHYDROXY-2-PROPOXY)METHYL]GUANINE - A NEW POTENT AND SELECTIVE ANTIHERPES AGENT
MARTIN, JC
DVORAK, CA
SMEE, DF
MATTHEWS, TR
VERHEYDEN, JPH
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1983, 26 (05) : 759 - 761
[37] 3-MEMBERED RINGS - THE PREPARATION OF SOME 1,2-CYCLOPROPANEDICARBOXYLIC ACIDS
MCCOY, LL
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1959, 80 (24) : 6568 - 6572
[38] MONTGOMERY JA, 1962, J MED CHEM, V5, P15, DOI 10.1021/jm01236a002
[39] A NEW ROUTE TO 1-SUBSTITUTED 3-CYCLOPENTENES
MURDOCK, KC
ANGIER, RB
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1962, 27 (07) : 2395 - &
[40] ALTERNATIVE APPROACHES TO 1-SUBSTUTED THYMINES
MURDOCK, KC
ANGIER, RB
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1962, 27 (09) : 3317 - &

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