EFFECTS OF INTRATHECAL BACLOFEN ON LUMBOSACRAL AND CORTICAL SOMATOSENSORY EVOKED-POTENTIALS

被引：15

作者：

KOFLER, M

DONOVAN, WH

LOUBSER, PG

BERIC, A

机构：

[1] HOSP JOINT DIS & MED CTR, DEPT NEUROL, 301 E 17TH ST, NEW YORK, NY 10003 USA

[2] UNIV INNSBRUCK, DEPT NEUROL, A-6020 INNSBRUCK, AUSTRIA

[3] UNIV INNSBRUCK, DEPT PHYS MED & REHABIL, A-6020 INNSBRUCK, AUSTRIA

[4] BAYLOR COLL MED, DIV RESTORAT NEUROL & HUMAN NEUROBIOL, HOUSTON, TX 77030 USA

来源：

NEUROLOGY | 1992年 / 42卷 / 04期

关键词：

D O I：

10.1212/WNL.42.4.864

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We analyzed lumbosacral and cortical somatosensory evoked potentials in three spinal cord injury patients undergoing evaluation of intrathecal baclofen infusion for management of spasticity. The cauda equina propagating root wave (R wave) and conus medullaris postsynaptic responses (S and P waves) were analyzed before and during baclofen infusion. Baclofen abolished the concomitantly recorded H-reflex and markedly suppressed the P wave amplitude and area. The S wave amplitude and area were suppressed to a lesser degree. In contrast, there were no significant changes in cortical somatosensory evoked potentials.

引用

页码：864 / 868

页数：5

共 26 条

[21] SURFACE RECORDING OF THE SPINAL VENTRAL ROOT DISCHARGE IN MAN - AN EXPERIMENTAL-STUDY [J].