HALICYLINDROSIDES, ANTIFUNGAL AND CYTOTOXIC CEREBROSIDES FROM THE MARINE SPONGE HALICHONDRIA-CYLINDRATA

被引:69
作者
LI, HY [1 ]
MATSUNAGA, S [1 ]
FUSETANI, N [1 ]
机构
[1] UNIV TOKYO, FAC AGR, MARINE BIOCHEM LAB, BUNKYO KU, TOKYO 113, JAPAN
关键词
D O I
10.1016/0040-4020(94)01097-J
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Ten new glycosphingolipids, halicylindrosides A(1)-A(4) (1-4) and B-1-B-6 (5-10) have been isolated from the Japanese marine sponge Halichondria cylindrata. Their structures were determined by spectroscopic and chemical methods. These cerebrosides were moderately antifungal against Mortierella remanniana, and cytotoxic against P388 murine leukemia cells.
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页码:2273 / 2280
页数:8
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