PULSATILE 2-DIMENSIONAL FLOW AND PLAQUE-FORMATION IN A CAROTID-ARTERY BIFURCATION

被引:31
作者
NAZEMI, M [1 ]
KLEINSTREUER, C [1 ]
ARCHIE, JP [1 ]
机构
[1] N CAROLINA STATE UNIV,DEPT MECH & AEROSP ENGN,RALEIGH,NC 27695
关键词
D O I
10.1016/0021-9290(90)90318-W
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
Velocity and pressure fields, streamlines and wall shear stress distributions were numerically obtained for two-dimensional, steady and pulsatile flow in a carotid artery segment. Distinct regions of reverse flow near the bifurcation and wavy flow patterns in the branching channels were observed during portions of the pulse. These phenomena disappear at the end of the systolic phase of the cardiac cycle. A previously validated plaque formation model predicts that plaque sites and the local extent of atherosclerotic lesions are similar for those present on human angiograms. © 1990.
引用
收藏
页码:1031 / 1037
页数:7
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