STRATEGIES AND TACTICS FOR FREE-RADICAL CARBOCYCLIZATION - SYNTHESIS OF POLYFUNCTIONALIZED CYCLOPENTANOID MOLECULES FROM CARBOHYDRATES

被引：33

作者：

MARCOCONTELLES, J

RUIZ, P

MARTINEZ, L

MARTINEZGRAU, A

机构：

来源：

TETRAHEDRON | 1993年 / 49卷 / 30期

关键词：

D O I：

10.1016/S0040-4020(01)81837-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The tributyltin hydride + azobisisobutyronitrile (AIBN) mediated free radical carbocyclization of precursors 1-9, 48 and 49 is described. The resulting carbocycles have been obtained in moderate yield and good diastereoselectivity. These polyfunctionalized, enantiomerically pure cyclopentane derivatives are useful intermediates for further manipulation.

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页码：6669 / 6694

页数：26

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