EFFECTS OF DIETHYL ETHER AND THYMOL ON ULTRASTRUCTURAL AND BIOCHEMICAL PROPERTIES OF PURIFIED SARCOPLASMIC RETICULUM FRAGMENTS FROM SKELETAL MUSCLE

被引：13

作者：

GREASER, ML

CASSENS, RG

HOEKSTRA, WG

BRISKEY, EJ

机构：

[1] Departments of Biochemistry and of Meat and Animal Science, University of Wisconsin, Madison, WI

来源：

BIOCHIMICA ET BIOPHYSICA ACTA | 1969年 / 193卷 / 01期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1016/0005-2736(69)90060-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

1. 1. Studies were conducted to determine if the biochemical alterations of sarcoplasmic reticulum fragments produced by diethyl ether or thymol treatment were related to the membrane ultrastructure. 2. 2. Concentrations of diethyl ether or thymol that abolished Ca2+-accumulating ability but did not reduce the Ca2+-activated ATPase activity caused the formation of transparent patches on the surface of negatively stained vesicles. 3. 3. Higher concentrations of diethyl ether or thymol caused a decrease in the Ca2+-activated ATPase activity, an apparent loss of the 40- A ̊ subunits and an increased irregularity in the vesicle surface structure. The vesicle shapes observed in sectioned preparations were also altered. © 1969.

引用

页码：73 / &

共 19 条

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PEACHEY, LD
[J]. JOURNAL OF CELL BIOLOGY, 1965, 25 (3P2) : 209 - &
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