COMPUTER-SIMULATION OF A CYTOSOLIC CALCIUM OSCILLATOR

被引:49
作者
SWILLENS, S
MERCAN, D
机构
[1] Inst. Rech. Interdisciplinaire, Universite Libre de Bruxelles, Campus Erasme, 1070 Brussels
关键词
D O I
10.1042/bj2710835
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
A new interpretation of existing data permits us to define a model capable of accounting for agonist-induced Ca2+ oscillations in the cytosol of electrically non-excitable cells. The model only requires one Ca2+ store, which contains Ca2+ channels controlled by inositol 1,4,5-trisphosphate and Ca2+. Computer simulations may generate different experimentally observed patterns of Ca2+ oscillations.
引用
收藏
页码:835 / 838
页数:4
相关论文
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