PRODUCTION OF HUMAN-ANTIBODIES USING BACTERIOPHAGE

被引：38

作者：

GRIFFITHS, AD

机构：

[1] MRC Centre for Protein Engineering, MRC Centre, Cambridge

来源：

CURRENT OPINION IN IMMUNOLOGY | 1993年 / 5卷 / 02期

关键词：

D O I：

10.1016/0952-7915(93)90015-K

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The immune system produces antibodies by a process of antigen-driven selection. An in vitro process of antigen-driven selection, based on the display of antibody fragments on filamentous bacteriophage, has recently been developed. This enables human antibody fragments of high affinity and specificity to be produced without immunization.

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页码：263 / 267

页数：5

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