CHEMICAL STUDY OF FATTY ACIDS WITH ANTITUMOR ACTIVITY ISOLATED FROM FUNGAL MYCELIA - STUDIES ON ANTIVIRAL AND ANTITUMOR ANTIBIOTICS .8.

被引:15
作者
ANDO, K
KATO, A
TAMURA, G
ARIMA, K
机构
[1] Laboratory of Microbiology, Department of Agricultural Chemistry, University of Tokyo, Tokyo
关键词
D O I
10.7164/antibiotics.22.23
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
The isolation of antitumor active oily substances from the mycelia of Penicillium crustosum, Penicillium tardum, Cephalosporium diospyri and Sepedonium ampullosprum has been described previously. The present paper describes chemical studies on these active products. Their infrared absorption spectra were virtually identical and were typical of long-chain fatty acids. Nuclear magnetic resonance spectra confirmed the presence of long-chain methylene and methylene interrupted double bonds. Mass spectra and the gas chromatographic studies of the methyl esters indicated the presence of palmitic, octadecaenoic and octadecadienoic acids as major constituents. © 1969, JAPAN ANTIBIOTICS RESEARCH ASSOCIATION. All rights reserved.
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页码:23 / &
相关论文
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JOURNAL OF ANTIBIOTICS, 1969, 22 (01) :18-&
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