TRANSITION-METAL-CATALYZED DIMERIZATION OF ALLENYL KETONES

被引：154

作者：

HASHMI, ASK

机构：

[1] Institut für Organische Chemie der Freien Universität, Berlin, D-14195

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH | 1995年 / 34卷 / 15期

关键词：

ALLENES; FURANS; PALLADIUM COMPOUNDS;

D O I：

10.1002/anie.199515811

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Astounding regioselectivity and good yields of the 2,4‐disubstituted furans 2 are obtained by the Pd‐catalyzed cycloisomerization/dimerization of readily accessible terminal allenyl ketones 1 (R = alkyl, aryl). Compounds 2 are formed exclusively with an (E)‐configurated trisubstituted double bond at C4. Remarkably, the allenyl ketones 1 with R = α‐haloalkyl and iodoaryl react smoothly to give 2. (Figure Presented.) Copyright © 1995 by VCH Verlagsgesellschaft mbH, Germany

引用

页码：1581 / 1583

页数：3

共 34 条

[31] INTRAMOLECULAR ENYNE METATHESIS REACTION - ROUTE TO BRIDGED BICYCLES WITH BRIDGEHEAD OLEFINS [J].