PRELIMINARY STRUCTURE DETERMINATION OF THE CAPSULAR POLYSACCHARIDE OF VIBRIO-CHOLERAE O139 BENGAL AL1837

被引：36

作者：

PRESTON, LM

XU, QW

JOHNSON, JA

JOSEPH, A

MANEVAL, DR

HUSAIN, K

REDDY, GP

BUSH, CA

MORRIS, JG

机构：

[1] UNIV MARYLAND,DEPT CHEM & BIOCHEM,BALTIMORE,MD 21228

[2] UNIV MARYLAND,VET AFFAIRS MED CTR,SCH MED,BALTIMORE,MD 21201

[3] UNIV MARYLAND,SCH MED,DEPT MED,BALTIMORE,MD 21201

[4] UNIV MARYLAND,SCH MED,DEPT PATHOL,BALTIMORE,MD 21201

[5] UNIV MARYLAND,SCH MED,CTR VACCINE DEV,BALTIMORE,MD 21201

[6] UNIV MARYLAND,SCH MED,CTR VACCINE DEV,BALTIMORE,MD 21201

来源：

JOURNAL OF BACTERIOLOGY | 1995年 / 177卷 / 03期

关键词：

D O I：

10.1128/jb.177.3.835-838.1995

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Vibrio cholerae O139 Bengal has recently been identified as a cause of epidemic cholera in Asia. In contrast to V. cholerae O1, V. cholerae O139 Bengal has a polysaccharide capsule. As determined by high-performance anion-exchange chromatography and H-1 nuclear magnetic resonance analysis, the capsular polysaccharide of V. cholerae O139 Bengal strain A11837 has six residues in the repeating subunit; this includes one residue each of N-acetylglucosamine, N-acetylquinovosamine (QuiNAc), galacturonic acid (GalA), and galactose and two residues of 3,6 -dideoxyxylohexose (Xylhex). The proposed structure is [GRAPHICS] the pro-S hydrogen.

引用

页码：835 / 838

页数：4

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