EVALUATION OF UW SOLUTION IN A RAT-KIDNEY PRESERVATION MODEL .1. EFFECT OF HYDROXYETHYL STARCH AND ELECTROLYTE-COMPOSITION

被引：42

作者：

BIGUZAS, M ^{[1
]}

JABLONSKI, P ^{[1
]}

THOMAS, AC ^{[1
]}

WALLS, K ^{[1
]}

HOWDEN, BO ^{[1
]}

SCOTT, DF ^{[1
]}

MARSHALL, VC ^{[1
]}

机构：

[1] MONASH UNIV,PRINCE HENRYS HOSP,DEPT SURG,ST KILDA RD,MELBOURNE,VIC 3004,AUSTRALIA

来源：

TRANSPLANTATION | 1990年 / 49卷 / 05期

关键词：

D O I：

10.1097/00007890-199005000-00006

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Preservation of rat kidneys by simple ice-storage has been demonstrated after 48 hr using the University of Wisconsin (UW) solution; hypothermic preservation of the rat kidney was dramatically improved. A modified UW solution without hydroxyethyl starch (HES) also gave uniform survival after 48 hr of storage, and even better function and morphology. Substitution of HES from another source also improved renal function when compared with UW (Dupont) and it is suggested that prolonged storage of UW solution prior to use may reduce its effectiveness. Reversing the Na:K ratio of the solution still allowed successful preservation, but significantly worsened morphology of the surviving kidney. © 1990 by Williams & Wilkins.

引用

页码：872 / 875

页数：4