OXYGEN RADICAL FORMATION AND DNA DAMAGE DUE TO ENZYMATIC REDUCTION OF BLEOMYCIN-FE(III)

被引：23

作者：

MAHMUTOGLU, I

SCHEULEN, ME

KAPPUS, H

机构：

[1] FREE UNIV BERLIN,FACHBEREICH 3,WE 15,RUDOLF VIRCHOW CLIN,AUGUSTENBURGER PLATZ 1,D-1000 BERLIN 65,FED REP GER

[2] UNIV ESSEN GESAMTHSCH,DEPT INTERNAL MED,D-4300 ESSEN 1,FED REP GER

来源：

ARCHIVES OF TOXICOLOGY | 1987年 / 60卷 / 1-3期

关键词：

D O I：

10.1007/BF00296969

中图分类号：

R99 [毒物学（毒理学）];

学科分类号：

100405 ;

摘要：

引用

页码：150 / 153

页数：4

共 27 条

[11] SUPEROXIDE-DEPENDENT FORMATION OF HYDROXYL RADICALS IN THE PRESENCE OF IRON SALTS - DETECTION OF FREE IRON IN BIOLOGICAL-SYSTEMS BY USING BLEOMYCIN-DEPENDENT DEGRADATION OF DNA
GUTTERIDGE, JMC
ROWLEY, DA
HALLIWELL, B
[J]. BIOCHEMICAL JOURNAL, 1981, 199 (01) : 263 - 265
[12] MOLECULAR ASPECTS OF CATECHOL AND PYROGALLOL INHIBITION OF LIVER MICROSOMAL LIPID PEROXIDATION STIMULATED BY FERROUS ION-ADP-COMPLEXES OR BY CARBON-TETRACHLORIDE
KAPPUS, H
KIECZKA, H
SCHEULEN, M
REMMER, H
[J]. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 1977, 300 (02) : 179 - 187
[13] KAPPUS H, 1982, MICROSOMES DRUG OXID, P555
[14] KAPPUS H, 1986, BIOL REACTIVE INTERM, V3, P273
[15] BLEOMYCIN MAY BE ACTIVATED FOR DNA CLEAVAGE BY NADPH CYTOCHROME-P-450 REDUCTASE
KILKUSKIE, RE
MACDONALD, TL
HECHT, SM
[J]. BIOCHEMISTRY, 1984, 23 (25) : 6165 - 6171
[16] OXY RADICAL FORMATION DURING REDOX CYCLING OF THE BLEOMYCIN IRON(III) COMPLEX BY NADPH-CYTOCHROME-P-450 REDUCTASE
MAHMUTOGLU, I
KAPPUS, H
[J]. BIOCHEMICAL PHARMACOLOGY, 1985, 34 (17) : 3091 - 3094
[17] PEPIN JM, 1985, BIOCHEM PHARMACOL, V34, P2386
[18] POVIRK LF, 1983, TOPICS MOL STRUCTURA, V3, P157
[19] IS THERE A ROLE FOR NUCLEI IN THE METABOLISM OF XENOBIOTICA - A REVIEW
ROMANO, M
FACCHINETTI, T
SALMONA, M
[J]. DRUG METABOLISM REVIEWS, 1983, 14 (04) : 803 - 829
[20] PERINATAL-DEVELOPMENT OF CYTOCHROME-P-450, NADPHCYTOCHROME-C REDUCTASE AND ETHOXYCOUMARIN DEETHYLASE IN RAT-LIVER NUCLEAR-MEMBRANES
ROMANO, M
CLOS, V
ASSAEL, BM
SALMONA, M
[J]. CHEMICO-BIOLOGICAL INTERACTIONS, 1982, 42 (02) : 225 - 231

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