PLASMODIUM-FALCIPARUM - 3 AMINO-ACID CHANGES IN THE DIHYDROFOLATE-REDUCTASE OF A PYRIMETHAMINE-RESISTANT MUTANT

被引：12

作者：

INSELBURG, J

BZIK, DJ

LI, WB

机构：

来源：

EXPERIMENTAL PARASITOLOGY | 1988年 / 67卷 / 02期

关键词：

D O I：

10.1016/0014-4894(88)90083-5

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

引用

页码：361 / 363

页数：3

共 12 条

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[2] MOLECULAR-CLONING AND SEQUENCE-ANALYSIS OF THE PLASMODIUM-FALCIPARUM DIHYDROFOLATE-REDUCTASE THYMIDYLATE SYNTHASE GENE [J].

BZIK, DJ ;

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[4]

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SCIENCE, 1986, 231 (4742) :1123-1128

[6] PYRIMETHAMINE RESISTANT PLASMODIUM-FALCIPARUM - OVERPRODUCTION OF DIHYDROFOLATE-REDUCTASE BY A GENE DUPLICATION [J].

INSELBURG, J ;

BZIK, DJ ;

HORII, T .

MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 1987, 26 (1-2) :121-134

[7] MECHANISM OF PYRIMETHAMINE RESISTANCE IN RECENT ISOLATES OF PLASMODIUM-FALCIPARUM [J].

MCCUTCHAN, TF ;

WELSH, JA ;

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[8] A NEW PAIR OF M13 VECTORS FOR SELECTING EITHER DNA STRAND OF DOUBLE-DIGEST RESTRICTION FRAGMENTS [J].

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VIEIRA, J .

GENE, 1982, 19 (03) :269-276

[9] KINETIC AND MOLECULAR-PROPERTIES OF DIHYDROFOLATE-REDUCTASE FROM PYRIMETHAMINE-SENSITIVE AND PYRIMETHAMINE-RESISTANT PLASMODIUM-CHABAUDI [J].

SIRAWARAPORN, W ;

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MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 1984, 10 (03) :355-367

[10] DIRECTED MUTAGENESIS OF DIHYDROFOLATE-REDUCTASE [J].

VILLAFRANCA, JE ;

HOWELL, EE ;

VOET, DH ;

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OGDEN, RC ;

ABELSON, JN ;

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