NEUROPATHY, AMYLOIDOSIS, AND MONOCLONAL GAMMOPATHY

被引：31

作者：

FITTING, JW ^{[1
]}

BISCHOFF, A ^{[1
]}

REGLI, F ^{[1
]}

CROUSAZ, GD ^{[1
]}

机构：

[1] UNIV BERN,DEPT NEUROL,CH-3000 BERN,SWITZERLAND

来源：

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY | 1979年 / 42卷 / 03期

关键词：

D O I：

10.1136/jnnp.42.3.193

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Three cases of neuropathy with monoclonal gammopathy and amyloid deposits in peripheral nerves are described. They appeared to present a benign gammopathy because of the duration of the neuropathy in the absence of any clinical or biological sign of myeloma or macroglobulinaemia. The pathological abnormality found in the sural nerves of the three patients was characterised by a marked loss of myelinated and unmyelinated nerve fibres because of active axonal degeneration with Wallerian degeneration. The most striking feature in all three cases was the finding of deposits identified as an accumulation of microfibrils.

引用

页码：193 / 202

页数：10

共 32 条

[1]

AMEIS A, 1976, CAN MED ASSOC J, V114, P889

[2] A PECULIAR FORM OF PERIPHERAL NEUROPATHY - FAMILIAR ATYPICAL GENERALIZED AMYLOIDOSIS WITH SPECIAL INVOLVEMENT OF THE PERIPHERAL NERVES [J].