RELAXIVITY CORRECTED RESPONSE MODULATED EXCITATION (RME) - A T-2-CORRECTED TECHNIQUE ACHIEVING SPECIFIED MAGNETIZATION PATTERNS FROM AN RF PULSE AND A TIME-VARYING MAGNETIC-FIELD

We have reworked the theory of RF excitation to enable correction for relaxivity while designing response-modulated excitation (RME) to achieve specified magnetization targets. This results in a significant improvement in the ability to achieve a specified target magnetization, especially if excitation time is long or T-2 is short. The methods presented may also be used to improve the quality of spatial-spectral pulses as well as localized spectroscopy, real-time imaging, real-time localized velocity and noninvasive pressure measurement.