INITIATION OF HEPATOCARCINOGENESIS IN INFANT MALE B6C3F1 MICE BY N-HYDROXY-2-AMINOFLUORENE OR N-HYDROXY-2-ACETYLAMINOFLUORENE DEPENDS PRIMARILY ON METABOLISM TO N-SULFOOXY-2-AMINOFLUORENE AND FORMATION OF DNA (DEOXYGUANOSIN-8-YL)-2-AMINOFLUORENE ADDUCTS

被引：62

作者：

LAI, CC ^{[1
]}

MILLER, EC ^{[1
]}

MILLER, JA ^{[1
]}

LIEM, A ^{[1
]}

机构：

[1] UNIV WISCONSIN,SCH MED,MCARDLE LAB CANC RES,MADISON,WI 53706

来源：

CARCINOGENESIS | 1987年 / 8卷 / 03期

关键词：

D O I：

10.1093/carcin/8.3.471

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

收藏

页码：471 / 478

页数：8

相关论文

共 35 条

[11] P-32 POST-LABELING ANALYSIS OF NONRADIOACTIVE AROMATIC CARCINOGEN DNA ADDUCTS
GUPTA, RC
REDDY, MV
RANDERATH, K
[J]. CARCINOGENESIS, 1982, 3 (09) : 1081 - 1092
[12] IRVING CC, 1966, CANCER RES, V26, P1390
[13] REDUCED PYRIDINE NUCLEOTIDE-DEPENDENT N-HYDROXY AMINE OXIDASE AND REDUCTASE ACTIVITIES OF HEPATIC MICROSOMES
KADLUBAR, FF
MCKEE, EM
ZIEGLER, DM
[J]. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1973, 156 (01) : 46 - 57
[14] KADLUBAR FF, 1985, ACS SYM SER, V283, P341
[15] HEPATIC MACROMOLECULAR COVALENT BINDING OF THE HEPATOCARCINOGEN 2,6-DINITROTOLUENE AND ITS 2,4-ISOMER INVIVO - MODULATION BY THE SULFOTRANSFERASE INHIBITORS PENTACHLOROPHENOL AND 2,6-DICHLORO-4-NITROPHENOL
KEDDERIS, GL
DYROFF, MC
RICKERT, DE
[J]. CARCINOGENESIS, 1984, 5 (09) : 1199 - 1204
[16] KOKKINAKIS DM, 1986, P AM ASSOC CANC RES, V27, P119
[17] N-SULFOOXY-2-AMINOFLUORENE IS THE MAJOR ULTIMATE ELECTROPHILIC AND CARCINOGENIC METABOLITE OF N-HYDROXY-2-ACETYLAMINOFLUORENE IN THE LIVERS OF INFANT MALE C57BL/6J X C3H-HEJ F1 (B6C3F1) MICE
LAI, CC
MILLER, JA
MILLER, EC
LIEM, A
[J]. CARCINOGENESIS, 1985, 6 (07) : 1037 - 1045
[18] LOTLIKAR PD, 1965, CANCER RES, V25, P1743
[19] MAHER VM, 1980, P AM ASSOC CANC RES, V21, P71
[20] MEERMAN JHN, 1980, CANCER RES, V40, P3772

← 1 2 3 4 →