SYNTHESIS OF DOUBLY AND MULTIPLY ISOTOPICALLY LABELED RETINALS

被引:34
作者
GROESBEEK, M [1 ]
LUGTENBURG, J [1 ]
机构
[1] LEIDEN UNIV, GORLAEUS LABS, DEPT CHEM, POB 9502, 2300 RA LEIDEN, NETHERLANDS
关键词
D O I
10.1111/j.1751-1097.1992.tb09711.x
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
In this paper a consecutive synthetic scheme is described that allows the synthesis of multiply C-13 labeled retinals with labels in the conjugated chain. This scheme can be extended to incorporation of H-2 labels in the conjugated chain. Also carotenoids can be multiply C-13 labeled with this strategy. The same approach has been used to label amino acids.
引用
收藏
页码:903 / 908
页数:6
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