CRYSTALLIZATION OF A TYPE-II DEHYDROQUINASE FROM MYCOBACTERIUM-TUBERCULOSIS

被引:36
作者
GOURLEY, DG
COGGINS, JR
ISAACS, NW
MOORE, JD
CHARLES, IG
HAWKINS, AR
机构
[1] UNIV GLASGOW, DEPT BIOCHEM, GLASGOW G12 8QQ, SCOTLAND
[2] UNIV GLASGOW, DEPT CHEM, GLASGOW G12 8QQ, SCOTLAND
[3] UNIV NEWCASTLE UPON TYNE, DEPT BIOCHEM & GENET, NEWCASTLE UPON TYNE NE2 4HH, ENGLAND
[4] WELLCOME RES LABS, DEPT CELL BIOL, BECKENHAM BR3 3BS, KENT, ENGLAND
关键词
SHIKIMATE; QUINATE PATHWAYS; 3-DEHYDROQUINASE; CRYSTALLIZATION;
D O I
10.1006/jmbi.1994.1524
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
A type II 3-dehydroquinase from Mycobacterium tuberculosis has been crystallized in the presence of 6% polyethyleneglycol 6000. Data from these crystals have been collected to a resolution of 2.2 Angstrom on a rotating anode X-ray source. The space group has been determined as F23 with unit cell dimensions of a=b=c=127.8 Angstrom . There is one molecule in the asymmetric unit.
引用
收藏
页码:488 / 491
页数:4
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