CRYSTALLIZATION OF A TYPE-II DEHYDROQUINASE FROM MYCOBACTERIUM-TUBERCULOSIS

被引：36

作者：

GOURLEY, DG

COGGINS, JR

ISAACS, NW

MOORE, JD

CHARLES, IG

HAWKINS, AR

机构：

[1] UNIV GLASGOW, DEPT BIOCHEM, GLASGOW G12 8QQ, SCOTLAND

[2] UNIV GLASGOW, DEPT CHEM, GLASGOW G12 8QQ, SCOTLAND

[3] UNIV NEWCASTLE UPON TYNE, DEPT BIOCHEM & GENET, NEWCASTLE UPON TYNE NE2 4HH, ENGLAND

[4] WELLCOME RES LABS, DEPT CELL BIOL, BECKENHAM BR3 3BS, KENT, ENGLAND

来源：

JOURNAL OF MOLECULAR BIOLOGY | 1994年 / 241卷 / 03期

关键词：

SHIKIMATE; QUINATE PATHWAYS; 3-DEHYDROQUINASE; CRYSTALLIZATION;

D O I：

10.1006/jmbi.1994.1524

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A type II 3-dehydroquinase from Mycobacterium tuberculosis has been crystallized in the presence of 6% polyethyleneglycol 6000. Data from these crystals have been collected to a resolution of 2.2 Angstrom on a rotating anode X-ray source. The space group has been determined as F23 with unit cell dimensions of a=b=c=127.8 Angstrom . There is one molecule in the asymmetric unit.

引用

页码：488 / 491

页数：4

共 34 条

[31] MOLECULAR-CLONING AND CHARACTERIZATION OF THE AROD GENE ENCODING 3-DEHYDROQUINASE FROM SALMONELLA-TYPHI [J].