RELATIONSHIP OF STRUCTURE OF EPIDERMIS TO PERCUTANEOUS ABSORPTION

被引：35

作者：

WINKELMANN, RK

机构：

[1] Section of Dermatology, Mayo Clinic and Mayo Foundation, Rochester, Minnesota

来源：

BRITISH JOURNAL OF DERMATOLOGY | 1969年 / S 81卷

关键词：

D O I：

10.1111/j.1365-2133.1969.tb16057.x

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

SUMMARY.— The epidermal barrier unit is composed of cells of the keratinocytic, transitional, and horny layers. The epidermis often contains other dendritic, leukocytic, and neural cells in the intercellular spaces. The epidermal intercellular canals and epidermal phagocytosis are 2 routes of transepidermal and transcorneal passage of materials. Individual, regional, age, and species differences in epidermis may account for variations in cutaneous permeability. Mitotic rate may be the most significant factor in barrier production. Copyright © 1969, Wiley Blackwell. All rights reserved

引用

页码：11 / +

页数：1