A REVIEW OF RECENT IMMUNOCHEMICAL STUDIES OF BLOMIA-TROPICALIS AND EUROGLYPHUS-MAYNEI ALLERGENS

被引：26

作者：

ARRUDA, LK

CHAPMAN, MD

机构：

[1] Division of Allergy and Clinical Immunology, Department of Medicine, University of Virginia, Charlottesville, 22908, VA

来源：

EXPERIMENTAL & APPLIED ACAROLOGY | 1992年 / 16卷 / 1-2期

关键词：

D O I：

10.1007/BF01201496

中图分类号：

Q96 [昆虫学];

学科分类号：

摘要：

Exposure to mites other than Dermatophagoides spp., particularly Blomia tropicalis and Euroglyphus maynei, has been increasingly recognized as a cause of asthma. Positive skin tests and serum IgE antibodies to B. tropicalis have been reported in asthmatic patients from several areas of the world, including Sao Paulo (Brazil), Hong Kong and Tampa (Florida, USA). Analysis of B. tropicalis extracts showed undetectable levels of the major Group I and Group II Dermatophagoides spp. allergens. Immunoabsorption experiments showed that most of the IgE antibodies to B. tropicalis (approximately 70%) reacted with species-specific allergens. Murine monoclonal antibodies to B. tropicalis could present antigens that were recognized by human IgG antibodies. Sensitization to E. maynei has been reported in Europe, North and South America and Australia. Analysis of four different E. maynei extracts by ELISA and RIA showed that E. maynei produces an allergen that is antigenically related to Dermatophagoides Group I allergens. The amino acid sequence of this allergen (Eur m I) has recently been reported. Further identification and purification of B. tropicalis and E. maynei allergens is required to develop specific assays for measuring these allergens in dust samples. This will make it possible to investigate the relationship between exposure to B. tropicalis or E. maynei and the development of sensitization and allergic disease.

引用

页码：129 / 140

页数：12

共 32 条

[1] Arlian L.G., Biology and ecology of house dust mites, Dermatophagoides spp. and Euroglyphus spp, Immunol. Allergy Clin. N. Am., 9, 2, pp. 339-356, (1989)
[2] Arruda L.K., Rizzo M.C., Chapman M.D., Fernandez-Caldas E., Baggio D., Platts-Mills T.A.E., Naspitz C.K., Exposure and sensitization to dust mite allergens among asthmatic children in São Paulo, Brazil, Clin. Exp. Allergy, 21, pp. 433-439, (1991)
[3] Blainey A.D., Topping M.D., Ollier S., Davies R.J., Allergic respiratory disease in grain workers: the role of storage mites, J. Allergy Clin. Immunol., 84, pp. 296-303, (1989)
[4] Blythe M.E., Some aspects of the ecological study of house dust mites, Br. J. Dis. Chest, 70, pp. 3-31, (1976)
[5] Burr M.L., Dean B.V., Merrett T.G., Neale E., St. Leger A.S., Verrier-Jones E.R., Effects of anti-mite measures on children with mite sensitive asthma: a controlled trial, Thorax, 35, pp. 506-512, (1980)
[6] Chapman M.D., Heyman P.W., Wilkins S.R., Brown M.J., Platts-Mills T.A.E., Monoclonal immunoassays for major dust mite (Dermatophagoides) allergens, Der p I and Der f I, and quantitative analysis of the allergen content of mite and house dust extracts, J. Allergy Clin. Immunol., 80, pp. 184-194, (1987)
[7] Colloff M.J., A review of biology and allergenicity of the house-dust mite Euroglyphus maynei (Acari: Pyroglyphidae), Exp. Appl. Acarol., 11, pp. 177-198, (1991)
[8] Colloff M.J., Population studies on the house dust mite, Euroglyphus maynei, (Cooreman 1950) (Pyroglyphidae), The Acari: Reproduction, Development and Life History Strategies, pp. 497-506, (1991)
[9] Colloff M.J., Stewart G.A., Thompson P.J., House dust acarofauna and Der p I equivalent in Australia: the relative importance of Dermatophagoides pteronyssinus and Euroglyphus maynei, Clin. Exp. Allergy, 21, pp. 225-230, (1991)
[10] Cuthbert O.D., Brostoff J., Wraith D.G., Brighton W.D., “Barn allergy”: asthma and rhinitis due to storage mites, Clin. Allergy, 9, pp. 229-236, (1979)

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