IMMEDIATE NOISE EFFECTS ON COCHLEAR VASCULATURE IN THE GUINEA-PIG

被引:55
作者
AXELSSON, A
VERTES, D
MILLER, J
机构
[1] SAHLGRENS HOSP, DEPT AUDIOL, S-41345 GOTHENBURG, SWEDEN
[2] SAHLGRENS HOSP, DEPT OTOLARYNGOL, S-41345 GOTHENBURG, SWEDEN
[3] UNIV WASHINGTON, DEPT OTOLARYNGOL, SEATTLE, WA 98195 USA
关键词
D O I
10.3109/00016488109138504
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
Nine guinea pigs were exposed to a 4 kHz narrow band noise at 120 dB for 30 min. The animals were killed immediately following exposure and the cochlear tissues prepared using a soft-surface preparation technique. Experimental and control animals were mixed and randomly assessed without prior knowledge of the groups to which the specimens belonged. The results were analyzed by computer. Statistically significant differences in the vasculature between noise-exposed and control animals of a general nature included: more changes in spiral lamina than external wall vessels, more changes in vessels facing perilymph than endolymph and more changes apically than basally. Results indicate slight intracochlear compensations in blood flow, that could potentially maintain a more constant circulation in regions of the cochlea corresponding to the 4 kHz narrow band exposure noise. Methodological aspects of this inner ear vascular technique as well as some hypothetical explanations regarding the observed changes in the blood supply are discussed.
引用
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页码:237 / 246
页数:10
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