CHARACTERIZATION OF A YEAST ARTIFICIAL CHROMOSOME FROM HUMAN-CHROMOSOME BAND 13Q12 CONTAINING THE FLT1 AND FLT3 RECEPTOR-TYPE TYROSINE KINASE GENES

被引：17

作者：

IMBERT, A ^{[1
]}

ROSNET, O ^{[1
]}

MARCHETTO, S ^{[1
]}

OLLENDORFF, V ^{[1
]}

BIRNBAUM, D ^{[1
]}

PEBUSQUE, MJ ^{[1
]}

机构：

[1] INSERM,U119,ONCOL MOLEC LAB,F-13009 MARSEILLE,FRANCE

来源：

CYTOGENETICS AND CELL GENETICS | 1994年 / 67卷 / 03期

关键词：

D O I：

10.1159/000133817

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

A yeast artificial chromosome containing the two receptor-type tyrosine kinase genes FLT1 and FLT3 was isolated, analyzed, and compared to a genomic map in order to establish their organization and linkage. FLT1 and FLT3 are physically linked in a head-to-tail configuration and separated by about 150 kb. The region contains three CpG islands. Two of them are likely to correspond to FLT1 and FLT3, whereas the third one is suggestive of another putative, unidentified RTK gene.

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页码：175 / 177

页数：3

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