NEW AND EFFICIENT SYNTHESIS OF E-4-DIETHOXYPHOSPHONYL-2-METHYL-2-BUTENAL AND OF ETHYL E-4-DIETHOXYPHOSPHONYL-2-METHYL-2-BUTENOATE, IMPORTANT BUILDING-BLOCKS IN RETINOID CHEMISTRY

被引：23

作者：

ALBADRI, H

ABOUTJAUDET, E

COLLIGNON, N

机构：

[1] INSA,COMPOSES ORGANOPHOSPHORES LAB,F-76131 MONT ST AIGNAN,FRANCE

[2] IRCOF,F-76131 MONT ST AIGNAN,FRANCE

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 03期

关键词：

D O I：

10.1016/0040-4039(94)02274-F

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Lithiated anion of diethyl alpha-trimethylsilyl-crotylphosphonate, in-situ generated from readily available diethyl crotylphosphonate, reacts smoothly with ethyl formate or ethyl chloroformate to give the title compounds 1 or 2, respectively, in high isolated yield.

引用

页码：393 / 396

页数：4

共 17 条

[1]

ALBADRI H, 1994, SYNTHESIS-STUTTGART, P1072

[2]

ALBADRI H, IN PRESS

[3]

BOROWIECKI L, 1982, LIEBIGS ANN CHEM, P1766

[4] A NEW VINYLIC ORGANOLITHIUM REAGENT - AN EXPEDIENT C-10+C-10 SYNTHESIS OF RETINAL [J].