SIGNAL-TRANSDUCTION EVENTS LEADING TO T-CELL LYMPHOKINE GENE-EXPRESSION

被引：153

作者：

FRASER, JD ^{[1
]}

STRAUS, D ^{[1
]}

WEISS, A ^{[1
]}

机构：

[1] UNIV CALIF SAN FRANCISCO,HOWARD HUGHES MED INST,DEPT MICROBIOL & IMMUNOL,SAN FRANCISCO,CA 94143

来源：

IMMUNOLOGY TODAY | 1993年 / 14卷 / 07期

关键词：

D O I：

10.1016/0167-5699(93)90236-E

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The expression of T-cell derived lymphokines is regulated by signal transduction events initiated by the T-cell antigen receptor and other T-cell surface molecules. Substantial progress has been made in characterizing the signal transduction events initiated at the Plasma membrane of the T cell and their targets which control lymphokine gene expression in the nucleus. This review will summarize recent progress in this area of investigation.

引用

页码：357 / 362

页数：6

共 69 条

[1] ENHANCEMENT OF T-CELL RESPONSIVENESS BY THE LYMPHOCYTE-SPECIFIC TYROSINE PROTEIN-KINASE P56LCK
ABRAHAM, N
MICELI, MC
PARNES, JR
VEILLETTE, A
[J]. NATURE, 1991, 350 (6313) : 62 - 66
[2] DEFECTIVE T-CELL RECEPTOR SIGNALING IN MICE LACKING THE THYMIC ISOFORM OF P59(FYN)
APPLEBY, MW
GROSS, JA
COOKE, MP
LEVIN, SD
QIAN, X
PERLMUTTER, RM
[J]. CELL, 1992, 70 (05) : 751 - 763
[3] CD28 INTERACTION WITH B7-COSTIMULATES PRIMARY ALLOGENEIC PROLIFERATIVE RESPONSES AND CYTOTOXICITY MEDIATED BY SMALL, RESTING LYMPHOCYTES-T
AZUMA, M
CAYABYAB, M
BUCK, D
PHILLIPS, JH
LANIER, LL
[J]. JOURNAL OF EXPERIMENTAL MEDICINE, 1992, 175 (02) : 353 - 360
[4] T-CELL RECEPTOR ACTIVATION OF A RIBOSOMAL S6 KINASE-ACTIVITY
CALVO, V
BIERER, BE
VIK, TA
[J]. EUROPEAN JOURNAL OF IMMUNOLOGY, 1992, 22 (02) : 457 - 462
[5] ZAP-70 - A 70 KD PROTEIN-TYROSINE KINASE THAT ASSOCIATES WITH THE TCR ZETA-CHAIN
CHAN, AC
IWASHIMA, M
TURCK, CW
WEISS, A
[J]. CELL, 1992, 71 (04) : 649 - 662
[6] NUCLEAR-LOCALIZATION AND REGULATION OF ERK-ENCODED AND RSK-ENCODED PROTEIN-KINASES
CHEN, RH
SARNECKI, C
BLENIS, J
[J]. MOLECULAR AND CELLULAR BIOLOGY, 1992, 12 (03) : 915 - 927
[7] IDENTIFICATION OF CALCINEURIN AS A KEY SIGNALING ENZYME IN LYMPHOCYTE-T ACTIVATION
CLIPSTONE, NA
CRABTREE, GR
[J]. NATURE, 1992, 357 (6380) : 695 - 697
[8] REGULATION OF T-CELL RECEPTOR SIGNALING BY A SRC FAMILY PROTEIN-TYROSINE KINASE (P59FYN)
COOKE, MP
ABRAHAM, KM
FORBUSH, KA
PERLMUTTER, RM
[J]. CELL, 1991, 65 (02) : 281 - 291
[9] CD5 IS PHOSPHORYLATED ON TYROSINE AFTER STIMULATION OF THE T-CELL ANTIGEN RECEPTOR COMPLEX
DAVIES, AA
LEY, SC
CRUMPTON, MJ
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1992, 89 (14) : 6368 - 6372
[10] STIMULATION OF THE PHOSPHATIDYL-INOSITOL PATHWAY CAN INDUCE T-CELL ACTIVATION
DESAI, DM
NEWTON, ME
KADLECEK, T
WEISS, A
[J]. NATURE, 1990, 348 (6296) : 66 - 69

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