CHROMATIN-MEDIATED TRANSCRIPTIONAL REPRESSION IN YEAST

被引：89

作者：

ROTH, SY

机构：

[1] Department of Biochemistry and Molecular Biology, University of Texas MD Anderson Cancer Center, Houston

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 1995年 / 5卷 / 02期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/0959-437X(95)80004-2

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Chromatin is linked to two modes of transcriptional repression in yeast: silencing at the HM loci and telomeres, and repression by the global regulator complex Ssn6/Tup1. In both cases, unique chromatin configurations appear to be orchestrated by multiprotein complexes targeted to particular regions through interactions with specific DNA-binding proteins, such as RAP1, the origin-recognition complex, and alpha 2.

引用

页码：168 / 173

页数：6

共 52 条

[1] OVERCOMING TELOMERIC SILENCING - A TRANSACTIVATOR COMPETES TO ESTABLISH GENE-EXPRESSION IN A CELL CYCLE-DEPENDENT WAY
APARICIO, OM
GOTTSCHLING, DE
[J]. GENES & DEVELOPMENT, 1994, 8 (10) : 1133 - 1146
[2] CARLSON M, 1984, GENETICS, V107, P19
[3] CHROMATIN TRANSITIONS DURING ACTIVATION AND REPRESSION OF GALACTOSE-REGULATED GENES IN YEAST
CAVALLI, G
THOMA, F
[J]. EMBO JOURNAL, 1993, 12 (12) : 4603 - 4613
[4] TARGETING OF SIR1 PROTEIN ESTABLISHES TRANSCRIPTIONAL SILENCING AT HM LOCI AND TELOMERES IN YEAST
CHIEN, CT
BUCK, S
STERNGLANZ, R
SHORE, D
[J]. CELL, 1993, 75 (03) : 531 - 541
[5] NOT1(CDC39), NOT2(CDC36), NOT3, AND NOT4 ENCODE A GLOBAL-NEGATIVE REGULATOR OF TRANSCRIPTION THAT DIFFERENTIALLY AFFECTS TATA-ELEMENT UTILIZATION
COLLART, MA
STRUHL, K
[J]. GENES & DEVELOPMENT, 1994, 8 (05) : 525 - 537
[6] THE GLOBAL TRANSCRIPTIONAL REGULATORS, SSN6 AND TUP1, PLAY DISTINCT ROLES IN THE ESTABLISHMENT OF A REPRESSIVE CHROMATIN STRUCTURE
COOPER, JP
ROTH, SY
SIMPSON, RT
[J]. GENES & DEVELOPMENT, 1994, 8 (12) : 1400 - 1410
[7] STIMULATION OF GAL4 DERIVATIVE BINDING TO NUCLEOSOMAL DNA BY THE YEAST SWI/SNF COMPLEX
COTE, J
QUINN, J
WORKMAN, JL
PETERSON, CL
[J]. SCIENCE, 1994, 265 (5168) : 53 - 60
[8] STATISTICAL POSITIONING OF NUCLEOSOMES BY SPECIFIC PROTEIN-BINDING TO AN UPSTREAM ACTIVATING SEQUENCE IN YEAST
FEDOR, MJ
LUE, NF
KORNBERG, RD
[J]. JOURNAL OF MOLECULAR BIOLOGY, 1988, 204 (01) : 109 - 127
[9] GOELB M, 1991, TRENDS BIOCHEM SCI, V16, P173
[10] TELOMERE-PROXIMAL DNA IN SACCHAROMYCES-CEREVISIAE IS REFRACTORY TO METHYLTRANSFERASE ACTIVITY INVIVO
GOTTSCHLING, DE
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1992, 89 (09) : 4062 - 4065

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